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  • Title: The effect of unilateral papillectomy on the juxtaglomerular granulated cells.
    Author: Szokol M, Baranyai E, Mikó I, Gomba S.
    Journal: Exp Pathol (Jena); 1977; 14(1-2):69-75. PubMed ID: 598457.
    Abstract:
    The changes of the juxtaglomerular index values in the superficial, deep and whole cortical areas of rat kidneys after unilateral papillectomy were analyzed. On the papillectomized side the JGI values showed an increase in the deep, and a decrease in the superficial cortical zone. The changes proved to be significant during the whole experimental period in the juxtamedullary index and between the 4--14 postoperative days in the superficial index values. The tendency of the changes of JGI in the contralateral kidneys was similar to those of the papillectomized kidneys, but significant differences were registered less constantly. These changes are probably the consequences of haemodynamic factors. Papillectomy is considered an incompetent model for studying the regulatory function of macula densa in the synthesis of renin.
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