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  • Title: Clomipramine (Anafranil) in depressive patients with obsessive neurosis.
    Author: Singh AN, Sexena B, Gent M.
    Journal: J Int Med Res; 1977; 5 Suppl 5():25-32. PubMed ID: 598603.
    Abstract:
    The authors express the view that, clinically, clomipramine (Anafranil, Geigy Pharmaceuticals) seems to be the treatment of choice for obsessive-compulsive illness. Clomipramine possesses a specific anti-obsessional property which is distinct from its antidepressant property. The optimal therapeutic dose from this study appears to be in the range of 175 mg to 225 mg a day. Minor reversible adverse reaction gradually decreases with the increase of duration of treatment.
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