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  • Title: Chronic double lumen intravenous cannulation of the unrestrained rat.
    Author: Brandstaetter J, Terkel J.
    Journal: Lab Anim Sci; 1977 Dec; 27(6):999-1003. PubMed ID: 599889.
    Abstract:
    Chronic double lumen intravenous cannulation was performed on the rat. The cannulation system consisted of a pulley assembly, protective tube, mounting post, and a double lumen cannula. Using a double lumen expanded catheter, a two-channel connection was made with the rat's vascular system through a single entry into the external jugular vein. The cannulation system permitted free animal movement in a large cage and simultaneous measurement of behavioral and physiologic variables. The procedure minimized stress and provided a simple alternative to other systems using two cannulas.
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