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  • Title: [The effect of D-penicillamine on experimental allergic arthritis in rabbits].
    Author: Püschel W, Rosenkranz M, Geiler G, Caffier B, Stiehl P, Richter V.
    Journal: Z Rheumatol; 1976; 35(5-6):201-9. PubMed ID: 60013.
    Abstract:
    The effect of D-penicillamine on experimental allergic arthritis in rabbits (16 with arthritis and 15 controls) was investigated. After 40 days of treatment with D-penicillamine (intravenous) the arthritis had receded to a large extent. At the same time a maturation inhibition of the hematopoietic marrow had occurred in all the treated arthritic and control animals. The results suggest that D-penicillamine affects fast proliferating cells, to which the precursors of immunologically active cells in the synovial membrane also belong.
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