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  • Title: Mesangial cell dysfunction detected by accumulation of aggregated protein in rats with streptozotocin induced diabetes.
    Author: Wardle EN.
    Journal: Biomedicine; 1975 Oct 20; 23(8):299-302. PubMed ID: 60145.
    Abstract:
    Diminished renal glomerular mesangial phagocytic function has been found in rats with streptozotocin induced diabetes. Similar impairment was produced by high dose cortisone and growth hormone, whereas oestrogen had a stimulant effect. The findings could be relevant to the understanding of human diabetic nephropathy.
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