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  • Title: [Uteroplacental blood flow in normal pregnancy before and after short-term treatment with (isoxsuprine) beta-sympathicomimetica (author's transl)].
    Author: Luotola H, Grönman P, Pitkänen M, Toivanen J, Pyörälä T.
    Journal: Z Geburtshilfe Perinatol; 1977 Dec; 181(6):407-12. PubMed ID: 602332.
    Abstract:
    The uteroplacental blood flow was measured in 26 normal pregnant women between the 36-43 weeks of pregnancy before and after a short-term treatment of isoxsuprine. The patients had no complications of pregnancy and no uterine contractions during this time. We used our intravenous Xe-133 method for measuring the intervillous and myometrial perfusion (20). During the blood flow measurements we also measured maternal arterial blood pressure and heart rate. To evaluate the short-term treatment effect of isoxsurpine we applied an intravenous injection or infusion. The placental flow was (124 +/- 32) before and (117 +/- 39) ml/min/100 ml after isoxsuprine application. The corresponding values for myometrial flow were (7,8 +/- 3,5) and (6,2 +/- 3,0) ml/min/100 g. The pathological changes of the uterplacental blood flow with vena caval syndrom will referred in text. There was a statistically significant increase in maternal heart rate and a decrease in blood pressure.
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