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  • Title: Strophanthidin-sensitive transport of cesium and sodium in muscle cells.
    Author: Sjodin RA, Beaugé LA.
    Journal: Science; 1967 Jun 02; 156(3779):1248-50. PubMed ID: 6025547.
    Abstract:
    Uptake of cesium-134 ions into muscle cells is reduced to very low values by the presence of 10(-5)M strophanthidin in the Ringer solution. Cesium ions can induce extrusion of sodium from muscle cells in which the intracellular sodium content is elevated. The cesium-induced extra efflux of sodium-22 is inhibited by the external presence of 10(-5)M strophanthidin. The coupling between inward movement of cesium and outward movement of sodium appears to be chemical in nature. The evidence suggests that cesium ions are transported into muscle cells by a system of sites or carriers that requires a source of metabolic energy for ion turnover to occur.
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