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  • Title: Intercellular gap junctions in the developing retina and pigment epithelium of the chick.
    Author: Hayes BP.
    Journal: Anat Embryol (Berl); 1977 Dec 02; 151(3):325-33. PubMed ID: 603084.
    Abstract:
    Gap junctions are found in the pigment epithelium, between retina and pigment epithelium and in the retina of 5-14 day chick embryos, they are identified using block staining and extracellular tracer techniques. In the pigment epithelium gap junctions are found between cell bodies and interdigitating processes and many change their position during development. Gap junctions between retina and pigment epithelium are only made by undifferentiated retinal ventricular cells and may provide intercytoplasmic pathways important for photoreceptor differentiation. Retinal gap junctions are found in an outer zone next to the pigment epithelium and inner zone near the vitreous, they are only seen between ventricular cells but may provide pathways for ganglion cell specification. The role of gap junctions in the generation of retinal neurons is discussed.
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