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  • Title: The interaction of aflatoxins with purines and purine nucleosides.
    Author: Clifford JI, Rees KR.
    Journal: Biochem J; 1967 May; 103(2):467-71. PubMed ID: 6032981.
    Abstract:
    From measurements of thermal hyperchromicity and the behaviour of an aflatoxin-DNA mixture on a Sephadex column it was concluded that aflatoxin B(1) is capable of weak binding to single-stranded DNA. The interactions of the aflatoxins (B(1), G(1) and G(2)) with nucleosides result in difference spectra and suggest that the purine bases and the amino group play a role in the binding of all the aflatoxins to DNA.
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