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  • Title: [Morphofunctional characteristics of the endocrine cells of the stomach following administration of hydrocortisone and L-thyroxine].
    Author: Fedchenko SN.
    Journal: Arkh Anat Gistol Embriol; 1977 Dec; 73(12):76-9. PubMed ID: 603411.
    Abstract:
    Electron microscopy with application of specific fluorescent histochemical reaction of Falck, as well as some methods of impregnation made it possible to indentify enterochromaffin cells in the stomach of hyperthyroid rats and the rats after cortisone injection under the conditions ox hyperfunction of the thyroid gland. After 20 days of L-thyroxin injection, and after 10 days of hydrocortisone injection, preceded by L-thyroxin, the amount of enterochromaffin cells in the epithelial layer of the gastric mucosa were noted to increase that was accompanied by simultaneous increase of the number of secretory argyrophil granules in their cytoplasm. Simultaneous injection of L-thyroxin and hydrocortisone, while not decreasing statistically significant amount of the cells, produced degradation of their cytoplasm.
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