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  • Title: Staging laparotomy with splenectomy in Hodgkin's disease.
    Author: Poulsen H, Bengmark S, Börjesson B, Flodgren P, Kallum B, Landberg T.
    Journal: Acta Chir Scand; 1977; 143(6):347-52. PubMed ID: 605734.
    Abstract:
    The series includes 91 patients with Hodgkin's disease who underwent a staging laparotomy with splenectomy during the years 1971-1976, in 82% of them as part of the initial evaluation before therapy. Positive abdominal lymph nodes were found in 29% of the patients, a positive spleen in 37%, and a positive liver in 10%. Follow-up of patients who lacked abdominal involvement at laparotomy indicate that sampling error was only of marginal importance. Evaluation of the therapeutic implications of the operation indicated that 41% of the patients benefited from the procedure; 31% by changing stage and 10% by changing radiation therapy port. Five patients had minor surgical complications. The mortality rate was nil.
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