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  • Title: Metabolism of 3H-testosterone in epididymis & accessory glands of reproduction in the castrate hamster Mesocricetus auratus.
    Author: Bose TK, Rajalakshmi M, Prasad MR.
    Journal: Indian J Exp Biol; 1977 Oct; 15(10):852-5. PubMed ID: 606649.
    Abstract:
    The metabolism of tritiated-testosterone in epididymis and accessory glands of reproduction was studied in the castrate hamster, Mesocricetus auratus. The amount of tritium accumulating in the epididymis was similar to that in the accessory glands 60 minutes postinjection but was significantly higher (p .02-p .001) at 150 minutes. In all accessory organs the rate of tritiated testosterone was slow; marked quantities of testosterone and androstanediol were present but the accumulation of dihydrotestosterone (DHT) was relatively minimal at both time intervals studied. These results may indicate a simultaneous requirement of testosterone and androstanediol to mediate the action of androgens in the hamster while DHT may be of secondary importance.
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