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  • Title: Pathological changes in small cerebral arteries causing occlusion and haemorrhage.
    Author: Russell RW.
    Journal: J Cardiovasc Pharmacol; 1984; 6 Suppl 4():S691-5. PubMed ID: 6083412.
    Abstract:
    The resistance arteries of the brain contain relatively small amounts of muscle and elastic tissue. As a result of chronic hypertension, the small arteries develop microaneurysms at points of least resistance. Plasma leaking into the damaged wall leads to lipohyaline change. The end-result is either occlusion of the artery, causing a lacunar infarct, or rupture, causing intracerebral haemorrhage.
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