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  • Title: [Experimental studies of the liberation of plasminogen activator by DDAVP].
    Author: Jablonowski C, Klöcking HP, Markwardt F.
    Journal: Folia Haematol Int Mag Klin Morphol Blutforsch; 1984; 111(4):567-74. PubMed ID: 6083928.
    Abstract:
    Infusion of 0,4 micrograms DDAVP/kg for 30 min increased the plasminogen activator activity in blood of experimental animals (dog, rat, rabbit). The plasminogen activator releasing effect was also demonstrated in isolated perfused vascular preparations (pig ear, rat lung) at low doses (10(-9) - 10(6) mol/l). According to these results DDAVP is believed to attack directly the endothelial cell.
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