These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Superoxide release by neutrophils: synergistic effects of a phorbol ester and a calcium ionophore.
    Author: Robinson JM, Badwey JA, Karnovsky ML, Karnovsky MJ.
    Journal: Biochem Biophys Res Commun; 1984 Jul 31; 122(2):734-9. PubMed ID: 6087812.
    Abstract:
    Exposure to combined suboptimal concentrations of 4 beta-phorbol 12-myristate 13-acetate and the calcium ionophore A23187 stimulates superoxide release from guinea pig neutrophils to rates ca. 3.5-fold greater than the sum of the rates elicited by each of the agents added separately. This effect was largely dependent upon the presence of calcium in the extracellular medium. The data are discussed in relation to recent reports concerning the interactions of phorbol-esters with cells and the mechanism of activation of superoxide release by neutrophils.
    [Abstract] [Full Text] [Related] [New Search]