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  • Title: Iron uptake from sialo transferrins by rat reticulocytes.
    Author: Dekker CJ, Kroos MJ, van der Heul C, van Eijk HG.
    Journal: Int J Biochem; 1984; 16(7):787-92. PubMed ID: 6088317.
    Abstract:
    Preparative isoelectric focusing of human diferric transferrin preparations yielded seven bands with different isoelectric points, due to differences in sialic acid content. Incubation of rat reticulocytes at 37 and 4 degrees C with differic preparations of four of these transferrin forms labeled with 59Fe and 125I show no differences in membrane binding of iron and transferrin and in iron uptake. Hence it is concluded that the carbohydrate chains are not directly involved in the process of iron delivery to reticulocytes.
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