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  • Title: The effect of zinc on [59Fe]lactoferrin binding to blood neutrophilic leucocytes and colostral cells.
    Author: Maneva AI, Manev VV, Sirakov LM.
    Journal: Int J Biochem; 1984; 16(7):793-7. PubMed ID: 6088318.
    Abstract:
    Zn2+ inhibits the binding of [59Fe]lactoferrin to neutrophilic leucocytes. The inhibiting effect is proportional to zinc concentration in the range 10-330 mumol/l. Zn2+ inhibits the [59Fe]lactoferrin binding to the colostral cells in the same degree as PMN. The inhibiting effect of Zn2+ on [59Fe]lactoferrin binding to neutrophilic leucocytes is equal to those of non-labelled lactoferrin and transferrin. Fe2+ and Cu2+ does not have such effect on binding of [59Fe]lactoferrin to the PMN leucocytes.
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