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  • Title: Dissociation of the functioning of a human parotid gland following trauma of the tympanic nerve (a pseudocolchicine phenomenon).
    Author: Levin SL.
    Journal: Int J Clin Pharmacol Res; 1983; 3(5):311-21. PubMed ID: 6088409.
    Abstract:
    In a group of patients with break-up of the tympanic nerve, restitution of unconditioned reflexes in a denervated parotid gland was accompanied with both an increased sensitivity to cholinergic agonists and a sharply perverted paradoxal secretory response to antagonists (atropine, scopolamine, metacine, chlorosile). The above phenomenon is similar to the syndrome resulting from the effect of colchicine on the nervous-muscle connection when, mediatory transmission remaining intact, a post-denervational increased sensitivity to mediators of cholinergic excitation is observed.
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