These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Contrasting effects of cytochrome C on the radiosensitivity of single-stranded phi X174 DNA in the presence of misonidazole or phenol under anoxia.
    Author: Lafleur MV, Pluijmackers-Westmijze EJ, Loman H.
    Journal: Int J Radiat Oncol Biol Phys; 1984 Aug; 10(8):1195-7. PubMed ID: 6088446.
    Abstract:
    The effect of misonidazole and cytochrome c on biologically active DNA was studied. In a solution of single-stranded phi X174 DNA the presence of both sensitizer and cytochrome c is needed to evoke radiosensitization. However, sensitizer or cytochrome c alone protects the DNA. Cytochrome c offers even an extra protection. The sensitization is dependent on the concentration of misonidazole. This finding opens up the possibility of studying sensitizers in a relatively simple system.
    [Abstract] [Full Text] [Related] [New Search]