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  • Title: Enkephalinergic-dopaminergic "reward" pathways: a critical substrate for the stimulatory, euphoric and memory-enhancing actions of alcohol--a hypothesis.
    Author: Esposito RU, Parker ES, Weingartner H.
    Journal: Subst Alcohol Actions Misuse; 1984; 5(2):111-9. PubMed ID: 6089362.
    Abstract:
    Recent evidence indicates that alcohol (ethanol) exerts specific effects on dopaminergic-enkephalinergic neuronal pathways which are involved with natural drive-induction and have also been implicated in reward and memory consolidation. It is proposed herein that the euphorigenic and "paradoxical" memory-enhancing effects of low doses of alcohol are related to its direct actions on this specific brain substrate.
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