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  • Title: Monosynaptic inhibition of phrenic motoneurons: a long descending projection from Bötzinger neurons.
    Author: Merrill EG, Fedorko L.
    Journal: J Neurosci; 1984 Sep; 4(9):2350-3. PubMed ID: 6090616.
    Abstract:
    Synaptic connections between medullary expiratory neurons and phrenic motoneurons were studied in anesthetized cats using spike-triggered averaging of synaptic noise in phrenic motoneurons. Monosynaptic inhibition of phrenic motoneurons originating from the rostral medullary expiratory neurons of the Bötzinger complex was revealed. Neither mono- nor disynaptic inhibition from expiratory neurons of the nucleus retroambigualis was found. It was concluded that Bötzinger complex expiratory neurons make long descending inhibitory connections with phrenic motoneurons: the expiratory neurons of the nucleus retroambigualis do not appear to make synaptic connections with phrenic motoneurons.
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