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  • Title: Effects of chronic noise or daily water restriction on the pituitary-adrenal axis in male rats.
    Author: Armario A, Castellanos JM, Balasch J.
    Journal: Rev Esp Fisiol; 1984 Jun; 40(2):153-7. PubMed ID: 6091189.
    Abstract:
    Pituitary-adrenal function was studied in male rats chronically stressed with noise as well as under water restriction regimen. Chronic noise did not modify either in vivo or in vitro corticoadrenal function. Daily water restriction decreased body weight and increased relative adrenal weight as well as the serum levels of ACTH and corticosterone. In vitro corticoadrenal responsiveness to ACTH was similar in control and water restricted rats. Thus, no evidence for increased adrenal sensitivity to ACTH in the pre-watering period was found in water restricted rats.
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