These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


PUBMED FOR HANDHELDS

Search MEDLINE/PubMed


  • Title: Shigella sonnei endotoxin reduces arterial blood pressure but does not alter pituitary pro-opiocortin cleavage and corticosterone release in the rat.
    Author: Saija A, Mondello F, Trimarchi GR, FocĂ  A, Costa G, Mastroeni P, Caputi AP.
    Journal: Res Commun Chem Pathol Pharmacol; 1984 Aug; 45(2):313-6. PubMed ID: 6091199.
    Abstract:
    Intravenous (iv) bolus injection of 320 and 640 micrograms/Kg of lipopolysaccharides (LPS) of S. sonnei (either in phase I or in phase II) resulted in a dose-dependent decrease in mean arterial pressure, when given in freely moving rats. No changes were observed in plasma beta-endorphin (beta-EP), ACTH and corticosterone levels. Pituitary beta-EP content was not modified 1 h after iv injection of LPS. Data suggest that doses of LPS, which are able to produce reversible hypotension, do not alter pro-opiocortin cleavage and corticosterone release.
    [Abstract] [Full Text] [Related] [New Search]