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  • Title: Release of cholecystokinin in response to food and intraduodenal fat in pigs, dogs and man.
    Author: Lilja P, Wiener I, Inoue K, Fried GM, Greeley GH, Thompson JC.
    Journal: Surg Gynecol Obstet; 1984 Dec; 159(6):557-61. PubMed ID: 6095475.
    Abstract:
    The present study was done to compare endogenous cholecystokinin-33 release in response to physiologic stimuli (meal, fat) in pigs, dogs and man. Plasma levels of cholecystokinin-33 were monitored using a radioimmunoassay for cholecystokinin which detects only cholecystokinin-33 and cholecystokinin-39. Ingestion of a meal caused release of cholecystokinin-33 within five, 20 and 120 minutes in man, pigs and dogs, respectively. Intraduodenal administration of corn oil resulted in a significant release of cholecystokinin-33 within 20 minutes in dogs, pigs and man.
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