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  • Title: Cyclic nucleotide changes and contractility in the rat anococcygeus muscle.
    Author: Saint DA, Nicol CJ.
    Journal: Res Commun Chem Pathol Pharmacol; 1984 Nov; 46(2):163-73. PubMed ID: 6096937.
    Abstract:
    The rat anococcygeus muscle can be activated by three different agonists, NA, ACh and KCl, each of these displaying a different degree of pharmacomechanical coupling. Investigation of cyclic nucleotide changes in the muscles when activated showed that changes in cAMP/cGMP ratio parallel changes in contractility. However, the cyclic nucleotide changes seem incidental to the process of contraction, rather than causally related to it.
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