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  • Title: Immunobiology of molar pregnancy and gestational trophoblastic tumors.
    Author: Berkowitz RS, Goldstein DP, Hoch EJ, Anderson DJ.
    Journal: J Reprod Med; 1984 Nov; 29(11):796-801. PubMed ID: 6097683.
    Abstract:
    Because all the chromosomes in complete molar pregnancy are of paternal origin, complete moles are complete allografts (transplants). Complete moles may therefore be expected to induce a vigorous maternal host immunologic response. Further understanding of the relationships between the normal placenta, mole and choriocarcinoma may provide important insights into the basic mechanisms of teratogenesis and carcinogenesis.
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