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  • Title: [Effect of hypercapnia on tyrosine and tryptophan metabolism].
    Author: Rudzit VK, Bumeĭster VK, Lerkh EE, Bol'shevich ZhA.
    Journal: Biull Eksp Biol Med; 1976; 81(4):416-8. PubMed ID: 6098.
    Abstract:
    Experiments were conducted on albino rats; it was revealed that an increase in CO2 content in the inspired air (3.8%) caused disturbances in tyrosine and tryptophane metabolism. The activity of tyrosine-aminotranspherase and of tryptophane-oxygenase proved to increase in the liver; blood serum displayed a reduced concentration of free tyrosine and free total tryptophane, but the level of free tryptophane obtained by dialysis proved to rise. A possible significance of these deviations in endogenous blastomogenesis is discussed.
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