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  • Title: Effect of carbon monoxide exposure on heart cytochrome c oxidase activity of rats.
    Author: Pankow D, Ponsold W.
    Journal: Biomed Biochim Acta; 1984; 43(10):1185-9. PubMed ID: 6098273.
    Abstract:
    The activity of cytochrome c oxidase in heart muscle of rats was within the control range 1 and 24 h after commencement of CO exposure (56% COHb) and was significantly decreased 3 h thereafter. A decrease of the enzyme activity was also detectable 3 h following repeated CO exposure demonstrating that cytochrome c oxidase does not seem to play a role in the adaptive response of organism to chronic CO exposure.
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