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  • Title: Amenorrhea-galactorrhea syndrome with craniopharyngioma.
    Author: Nakasu Y, Nakasu S, Handa J, Takeuchi J.
    Journal: Surg Neurol; 1980 Feb; 13(2):154-6. PubMed ID: 6101923.
    Abstract:
    Two cases of craniopharyngioma presenting with amenorrhea-galactorrhea syndrome due to hyperprolactinemia are reported. After operation and irradiation, the tumor reduced markedly in size. Coincidental decrease in plasma prolactin level and restoration of menstruation seem to support the view that the hypothalamic prolactin inhibiting factor (PIF) had played an important role in hyperprolactinemia in these two patients.
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