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  • Title: [Kinin system components and blood serum proteinase inhibitors in hemorrhagic fever with renal syndrome].
    Author: Obukhova GG.
    Journal: Vopr Med Khim; 1980; 26(1):118-20. PubMed ID: 6102827.
    Abstract:
    In polyuric period of hemorrhagic fever with renal syndrome a distinct activation of the kinin system was observed in blood serum of patients; it was manifested as an increase in spontaneous BAEE-esterase and kallikreine activities as well as a decrease in kininogen content. Content of inhibitors of proteinases (alpha 1-antitrypsin) was increased within all the periods of hemorrhagic fever with renal syndrome, beginning from the I preoligouric period. The data obtained suggest that kinins are involved in pathogenesis and clinical manifestations of hemorrhagic fever with the renal syndrome.
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