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  • Title: [Experience in using fenazepam to treat psychotic patients].
    Author: Nuller IuL, Tochilov VA.
    Journal: Zh Nevropatol Psikhiatr Im S S Korsakova; 1980; 80(6):914-20. PubMed ID: 6106340.
    Abstract:
    Fenazepam, a potent anxiolytic tranquillizer (7-brom-5/o-chlorphenyl/1,2-dihydro-3H-1,4-benzodiazepin-2-on) was used in the treatment of 173 psychotic patients ( schizophrenia, endogenous depressions, involutional and organic psychoses). In all cases the clinical picture was characterized by anxiety. In 37% of the patients the psychopathological symptomatology disappeared altogether, in 27% there was a significant improvement. The best results were attained in the treatment of anxious-depressive, depersonalization and affective-delusional states. Anxious-depressive conditions in endogenous depressions gave worse results during fenazepam treatment, than in schizophrenia and organic brain disorders. Affective-delusional attacks were arrested by fenazepam in the initial phases. A good effect was also seen in depersonalization.
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