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  • Title: Alterations of plasma high-density lipoprotein cholesterol levels associated with consumption of selected medications. The Lipid Research Clinics Program Prevalence Study.
    Author: Wallace RB, Hunninghake DB, Reiland S, Barrett-Connor E, Mackenthun A, Hoover J, Wahl P.
    Journal: Circulation; 1980 Nov; 62(4 Pt 2):IV77-82. PubMed ID: 6106533.
    Abstract:
    From the 10 North American study populations of the Lipid Research Clinics Program, mean levels of plasma high-density (HDL) cholesterol were contrasted between users of eight categories of prescribed medications and a control group of nonusers of those categories matched for age, sex, study population and ponderosity. Women taking propranolol had a mean HDL cholesterol level 12 mg/dl lower than nonusers (p < 0.05). Men taking phenytoin had a mean HDL cholesterol level more than 18 mg/dl higher than nonusers (p < 0.05). Men taking benzodiazepine derivatives had a mean HDL cholesterol level 3.3 mg/dl lower than nonusers (p < 0.05). No significant differences were found between users and nonusers of thiazide diuretics, chlorthalidone, barbiturates, sympathomimetics or antihistamines.
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