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  • Title: The emergence of ORG NC 45, 1- [2 beta,3 alpha,5 alpha,16 beta,17 beta)-3, 17-bis(acetyloxy)-2-(1-piperidinyl)-androstan-16-yl]-1-methylpiperidinium bromide, from the pancuronium series.
    Author: Savage DS, Sleigh T, Carlyle I.
    Journal: Br J Anaesth; 1980; 52 Suppl 1():3S-9S. PubMed ID: 6107102.
    Abstract:
    A novel approach is described for obtaining a drug that will be a potent non-depolarizing neuromuscular blocking agent with the potential for a short duration of action and little cumulative effect. This approach led to the discovery of Org NC 45, from the pancuronium series.
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