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  • Title: Reliable routine method for determination of perazine in serum by thin-layer chromatography with an internal standard.
    Author: Kresse M, Schley J, Müller-Oerlinghausen B.
    Journal: J Chromatogr; 1980 Oct 10; 183(4):475-82. PubMed ID: 6107303.
    Abstract:
    The use of a high-performance thin-layer chromatography linear chamber and of thioridazine as internal standard increases the performance of thin-layer chromatography (TLC) with direct densitometric scanning, and allows the rapid determination of serum levels of the neuroleptic drug perazine under usual therapeutic conditions. TLC is superior to gas-liquid chromatography in so far as the main metabolite desmethylperazine can be easily separated and detected by the same procedure.
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