These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Reduced amounts of immunoreactive somatostatin in the temporal cortex in senile dementia of Alzheimer type.
    Author: Rossor MN, Emson PC, Mountjoy CQ, Roth M, Iversen LL.
    Journal: Neurosci Lett; 1980 Dec; 20(3):373-7. PubMed ID: 6108540.
    Abstract:
    Post-mortem brain tissue from 15 patients dying with a diagnosis of senile dementia of Alzheimer type (SDAT) was compared with tissue obtained from 16 control patients at routine post-mortem. A significant fall in choline acetyltransferase (ChAT) activity was observed in the cortex, hippocampus and amygdala of the SDAT cases and was maximal in the temporal cortex. The fall in ChAT activity observed in the temporal cortex was accompanied by a significant reduction (47%) in immunoreactive somatostatin.
    [Abstract] [Full Text] [Related] [New Search]