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  • Title: Peptides and thermoregulation.
    Author: Yehuda S, Kastin AJ.
    Journal: Neurosci Biobehav Rev; 1980; 4(4):459-71. PubMed ID: 6110198.
    Abstract:
    Several peptides are now known to affect thermoregulation. These include beta-endorphin, bombesin, MIF-I, alpha-MSH, neurotensin, TRH, and DSIP. Some of these have been found to interact with the thermal effects of d-amphetamine, a drug with well established actions on thermoregulation. The effects of morphine on body temperature provide some notable comparisons with beta-endorphin, as do the similarities between the effects of naloxone and MIF-I. In general, it seems that two of the major variables which interact and modify the thermal effects of peptides are ambient temperature and route of administration.
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