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  • Title: Korean hemorrhagic fever: propagation of the etiologic agent in a cell line of human origin.
    Author: French GR, Foulke RS, Brand OA, Eddy GA, Lee HW, Lee PW.
    Journal: Science; 1981 Mar 06; 211(4486):1046-8. PubMed ID: 6110243.
    Abstract:
    The etiologic agent of Korean hemorrhagic fever has been propagated in a human cultured cell line derived from a carcinoma of the lung. The cells, described as type II, alveolar epithelial, support replication of the agent and successive passages. Antigen of the Korean hemorrhagic fever agent is readily detected in infected cells by means of direct or indirect fluorescent antibody techniques. Previous attempts to propagate this agent in vitro had been unsuccessful.
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