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  • Title: [Treatment of therapeutically resistant paranoid schizophrenic patients with Moditen-depot combined with other psychotropic drugs and Leponex].
    Author: Gamburg AL, Aranovich AG, Kotel'kevich IuN, Omorokov BM, Rasniuk VA.
    Journal: Zh Nevropatol Psikhiatr Im S S Korsakova; 1980; 80(8):1211-6. PubMed ID: 6111169.
    Abstract:
    The results of treating 251 therapeutically resistant patients with paranoid schizophrenia by moditen-depo, its combination with other psychotic drugs or leponex was compared. The results obtained indicate that a comprehensive treatment (moditen-depo with other psychotropic drugs) and by leponex may be successfully applied to some of the paranoid schizophrenics resistant to moditen-depo and other neuroleptic drugs or their combinations. Comprehensive treatment appeared to be more effective in systematized delusions, the syndrome of psychic automatisms and in a crude emotional-volitional defect. Treatment by leponex was more efficacious in emotionally saturated nonsystematized delusions, pronounced disordered behaviour and mild manifestation of deterioration.
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