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  • Title: A probable neuroleptic effect on platelet monoamine oxidase in chronic schizophrenic patients.
    Author: DeLisi LE, Wise CD, Bridge TP, Rosenblatt JE, Wagner RL, Morihisa J, Karson C, Potkin SG, Wyatt RJ.
    Journal: Psychiatry Res; 1981 Feb; 4(1):95-107. PubMed ID: 6111821.
    Abstract:
    Platelet monoamine oxidase activity (MAO) was studied serially over time in 16 chronic schizophrenic patients when medication free and then when medicated. Thirteen of the 16 patients had significant decreases in platelet MAO activity following neuroleptic drug treatment. The change in MAO activity was found to be correlated with response to treatment and to dose of medication.
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