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  • Title: [Changes in serum parameters after oral alcohol intake in healthy men].
    Author: Pöge AW, Brand G, Kothe W.
    Journal: Dtsch Z Verdau Stoffwechselkr; 1981; 41(1):34-41. PubMed ID: 6112129.
    Abstract:
    A short-time-study (1 to 24 hours) and a long-time-study (1 to 96 hours) after a single alcohol intake were made in 23 healthy probands. The pancreas and liver parameters as alpha-amylase, bilirubin, ASAT, ALAT, gamma-GT and GLDH in the serum were determined at regular intervals. The pancreas showed a sensitive reaction to alcohol expressed by an early rise of lipase activity. The liver enzymes of young healthy probands remained unchanged. Older probands, on the other hand, react by a distinct increase of the gamma-GT and GLDH as well as a decrease of the ASAT and ALAT. Also the enzyme quotients gamma-GT/ASAT and (ASAT + ALAT)/GLDH be obviously well suited to recognizing very early stages of liver lesion by serum examinations. For this purpose only a definite alcohol intake (I ml ethanol per kg body weight) is necessary.
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