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  • Title: Oral anti-microbial prophylaxis in colonic surgery.
    Author: Goldring JR, McNaught W, Gillespie G.
    Journal: Aktuelle Probl Chir Orthop; 1981; 19():101-4. PubMed ID: 6112906.
    Abstract:
    A combination of kanamycin and metronidazole administered for 3 days by mouth preoperatively, significantly suppresses both the aerobic and anaerobic colonic microflora, and significantly reduces the incidence of postoperative wound infection. During 6 years experience with this regimen, no toxic or untoward effects have been observed.
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