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  • Title: Bee venom enhances guanylate cyclase activity.
    Author: Vesely DL.
    Journal: Science; 1981 Jul 17; 213(4505):359-60. PubMed ID: 6113689.
    Abstract:
    Bee venom and phospholipase A2 extracted from bee venom enhanced guanylate cyclase (E.C. 4.6.1.2) activity two- to threefold in rat liver, lung, heart, kidney, ileum, and cerebellum. Dose-response relationships revealed that bee venom at concentrations as low as 1 microgram per milliliter and phospholipase A2 at 1 microunit per milliliter caused a maximal enhancement of guanylate cyclase.
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