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  • Title: [The diagnostic significance of countercurrent immunoelectrophoresis (CIE) in bacterial meningitis in children (author's transl)].
    Author: Roos R, Belohradsky BH.
    Journal: Monatsschr Kinderheilkd; 1981 Jun; 129(6):354-8. PubMed ID: 6114417.
    Abstract:
    In 52 children with meningitis caused by Hemophilus influenzae, pneumococci, meningococci and group B streptococci the organism responsible could be identified in 41 cases (79%) within one hour with specific antisera by means of countercurrent immunoelectrophoresis (CIE). False positive results were not observed in meningitis caused by other organisms, aseptic meningitis, septicemia, etc. In 4 cases the organism could only be identified by CIE since the children had received antibiotics and the culture was negative. Group B meningococci are often missed in CIE. CIE proved to be a valuable tool in diagnostic procedures of bacterial meningitis.
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