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  • Title: Determination of auto-antibodies against spermatozoa in experimental cryptorchism.
    Author: Rost A, Ehrenberg W, Fiedler U.
    Journal: Urol Int; 1981; 36(1):59-66. PubMed ID: 6114588.
    Abstract:
    In 70% of the patients with unilateral retentio testis the normal descended testicle shows damage in spermiogenesis too. The formation of auto-antibodies is considered as a possible cause. In rats with artificial uni- and bilateral cryptorchism, this mechanism was examined. The presence of auto-antibodies against spermatozoa could be proven by indirect immunofluorescence. After uni- and bilateral intra-abdominal displacement of the testicles, this phenomenon takes place after the 3rd month post-operatively, shows the maximum of titers after 6 months and decreases towards the 9th month post-operatively. An animal model is presented, suitable for the study of immunological processes in unilateral gonadal diseases.
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