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  • Title: Propoxyphene form maintenance treatment of narcotic addiction.
    Author: Woody GE, Mintz J, Tennant F, O'Brien CP, McLellan AT, Marcovici M.
    Journal: Arch Gen Psychiatry; 1981 Aug; 38(8):898-900. PubMed ID: 6114721.
    Abstract:
    Two studies compared propoxyphene napsylate (Darvon-N) with methadone hydrochloride as maintenance treatment for narcotic addicts. Most measures indicated that methadone was more effective than propoxyphene as a maintenance drug. Patients receiving propoxyphene reported more withdrawal-related symptoms early in treatment, tended to drop out sooner than patients receiving methadone, and were more likely to abuse heroin. Nevertheless, follow-up interviews at one and six months after treatment indicated no between-group differences in adjustment.
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