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  • Title: [Structuro-metabolic integration of gastric endocrine cells in the presence of a disruption in hormone balance].
    Author: Fedchenko SN.
    Journal: Arkh Anat Gistol Embriol; 1981 Mar; 80(3):68-77. PubMed ID: 6114727.
    Abstract:
    In experimentally hyperthyroid rats an increased amount of gastrin-producing (G) and histamine-producing (ECl) cells was noted by means of immunofluorescent biochemical methods and electron microscopically. Increased amount of the ECl cells was combined with a rise in histamine contents in the gastric mucosa. Hydrocortisone injections resulted in degranulation of the G- and ECl-cells. After hydrocortisone injection, the amount of histamine decreased more than two-fold. It was demonstrated that not only parietal glandulocytes, but also the gastric endocrine cells participated in disorders of a complex acid-producing mechanism.
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