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  • Title: The influence of foot-shock stress upon brain, pituitary and spinal cord pools of immunoreactive dynorphin in rats.
    Author: Millan MJ, Tsang YF, Prezewłocki R, Höllt V, Herz A.
    Journal: Neurosci Lett; 1981 Jun 12; 24(1):75-9. PubMed ID: 6115344.
    Abstract:
    The distribution of immunoreactive-dynorphin (ir-dyn) in the pituitary, discrete regions of brain and the spinal cord, and the influence of 5 min foot-shock stress (FS) upon levels of ir-dyn in these structures, were examined in rats. FS produced a significant fall in the anterior pituitary lobe (AL) content of ir-dyn but no significant change in its neurointermediate (NIL) counterpart. In the hypothalamus, in contrast, a significant elevation in levels of ir-dyn was observed. With the exception of the frontal cortex, in which a decrease in levels of ir-dyn was found, in all other brain regions examined no significant changes emerged. A significant diminution in concentrations of ir-dyn in both the lumbosacral and thoracic sections of the spinal cord was, however, detected.
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