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  • Title: [Changes of the tissue CO2 and O2 tension in the healing process of crushed muscles (author's transl)].
    Author: Józsa L, Réffy A, Demel Z, Szilágyi I.
    Journal: Magy Traumatol Orthop Helyreallito Seb; 1981; 24(1):48-51. PubMed ID: 6115965.
    Abstract:
    Silastic tonometer was implanted into the space between soleus and gastrocnemius muscles of the rat. When tissue O2 and CO2 tensions returned to normal, the muscles were crushed with the skin closed. The O2 tension in the muscles was found to decrease from 44 HGMM to 10-15 hgmm following the crush, and kept it until the 4th day. After the 5th day pO2 begins to increase on the 10th day it will reach the O2 tension of the intact muscle, and keeps increasing after the 10th day. Afterwards the muscular O2 tension begins to decrease, parallel with the development of granulation tissue and will return to the original rate on the 20th day post injury. Histological picture shows that regeneration has been completed by this time too.
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