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  • Title: [Efficacy of captopril in periarteritis nodosa with arterial hypertension and renal failure (author's transl)].
    Author: Guillevin L, Leenhardt A, Herson S, Bletry O, Godeau P.
    Journal: Nouv Presse Med; 1981 Apr 30; 10(19):1592-3. PubMed ID: 6116493.
    Abstract:
    In a patient with periarteritis nodosa failure of antihypertensive treatment with beta-blockers and diuretics encouraged the authors to use captopril in doses of 150 mg per day. Blood pressure rapidly returned to normal levels. The hypotensive effect of captopril is ascribable to its action on the renin-angiotensin system, since plasma renin activity was particularly high in this patients.
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