These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Changes in skin reactivity to phytohemagglutinin caused by general anesthesia].
    Author: Boileau S, Lancelot A, Laxenaire MC, Moneret-Vautrin DA.
    Journal: Ann Anesthesiol Fr; 1981; 22(3):231-4. PubMed ID: 6117227.
    Abstract:
    Cellular immunity is studied by intradermal reaction to phytohaemagglutinin (four concentrations: 1, 2, 5 and 10 infinity g), the response to which at the 24th hour gives information concerning macrophage power and at the 48th hour the functional value of the T lymphocytes. Such a study was carried out in three groups of patients: 1st group (n = 20): general anaesthesia without surgery, duration less than 30 minutes; 2nd group (n = 10): general anaesthesia without surgery, duration greater than 2 hours; 3rd group (n = 20): general anaesthesia with surgical procedure, duration greater than 2 hours. In all groups, the results showed highly significant immune depression at the 24th hour, certainly linked to a depression of macrophage power. This depression persisted at the 48th hour, but less markedly and less significantly, which could not be interpreted as definite evidence of depression of the T lymphocytes. Surgery would not appear to have played any additional role to anaesthesia in this immune depression, nor did the duration of anaesthesia. In a 4th group (n = 10) treated with vitamin A and undergoing anaesthesia with surgery lasting for more than two hours, no immune depression was seen.
    [Abstract] [Full Text] [Related] [New Search]